MELOXICAM SELF-NANOEMULSIFYING DRUG DELIVERY SYSTEM: FORMULATION AND RELEASE KINETICS ANALYSIS
نویسندگان
چکیده
Objective: This study aimed to find the best SNEDDS meloxicam formula and analyze release kinetics of non-SNEDDS using DDSolver. 
 Methods: Meloxicam was prepared sunflower seed oil, Cremophor RH 40 as a surfactant, polyethylene glycol (PEG) 400 co-surfactant. Results: The obtained subjected in vitro dissolution analyzed shows one selected consists 10% 70% cremophor 40, 20% PEG with 20.5 nm±12 nm droplet size. showed that could significantly increase compared formulation. from formulations follow Weibull model (β = 1.00). Conclusion: concludes seeds oil: Chremophor 40: ratio 1: 7: 2 has potency solubility meloxicam.
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ژورنال
عنوان ژورنال: International Journal of Applied Pharmaceutics
سال: 2021
ISSN: ['0975-7058']
DOI: https://doi.org/10.22159/ijap.2021.v13s4.43856